lookindex

PTD-DBM

Also known as CXXC5 blocking peptide

It regrew hair in mice, and the target protein is raised in balding human scalps. That is a promising lead, not evidence it works on your head.

Information only. Not medical advice. Talk to a doctor before you start, stop or change anything.

What people claim

  • Regrows hair follicles from scratch
  • A cure for baldness
  • Works where minoxidil failed

What the evidence shows

  • In a 2017 mouse study, applying it to the skin sped up hair regrowth, more so when combined with valproic acid.[1]
  • The same team found its target protein, CXXC5, raised in human balding scalp samples.[1]
  • The lead researcher is linked to a company developing the approach.[1]
  • Follow-up work from the same lab was also in mice.[2]

Known risks

  • Human safety has not been studied.
  • TGA testing found unapproved peptides often do not contain what their labels claim.[3]

Reported side effects

Moderated user reports are not open yet, so nothing is shown here. They will be labelled as unverified personal accounts.

Legal status

A summary, not legal advice. Rules change, and sport bans are separate.

United States

Unapproved

No approved medicine contains it.

United Kingdom

Unlicensed

No licensed medicine contains it.

Australia

Not approved

No approved medicine contains it.

European Union

Not authorised

No authorised medicine. National rules on possession and import differ.

Sources

  1. 1.Targeting of CXXC5 by a competing peptide stimulates hair regrowth and wound-induced hair neogenesisJournal of Investigative Dermatology, 2017
  2. 2.CXXC5 mediates DHT-induced androgenetic alopecia via PGD2Cells, 2023
  3. 3.TGA testing finds unapproved peptides do not contain what their labels claimTGA Australia, Nov 2026

Profile last checked 7 Nov 2026.